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Interestingly, GLP-1 is also known to decrease the rewarding effects of food intake by interacting with parts of the mesolimbic dopamine system such as the ventral tegmental area (VTA), nucleus accumbens (NAc) [34], and also GABAergic circuits in the laterodorsal tegmental nucleus (LDTg) [35], which makes brain GLP-1R signaling a promising target for the treatment of alcohol and cocaine abuse disorders [36, 37]

It is important to note that cross-trial comparisons have significant limitations

So, is Zepbound the same as Ozempic

Deutsch EW, Bandeira N, Perez-Riverol Y, Sharma V, Carver JJ, Mendoza L, Kundu DJ, Wang S et al (2023) The ProteomeXchange consortium at 10 years: 2023 update