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In the SURMOUNT-1 trial the highest dose produced about 20.9% mean weight loss over 72 weeks
Additionally, semaglutide failed to improve fibrosis in the study, casting doubt over whether it can tackle fibrosis
Bringing new therapies to market requires companies to conduct extensive, time-consuming, and expensive studies to demonstrate long-term safety and efficacy, particularly as these drugs expand into indications such as obesity and cardiovascular risk reduction
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