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It depends on the methionine cycle, including methionine, SAM, SAH and homocysteine

Supplement alternatives to ALA If youre exploring options beyond alpha-lipoic acid for nerve health or oxidative stress, two of the most studied and promising alternatives are vitamin B12 and acetyl-L-carnitine (ALCAR).56 Each plays a unique role in nerve protection and repair, particularly in the context of diabetic neuropathy