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The field has evolved from the 2-minute half-life of native GLP-1 to engineered analogs that persist for a week a 5,000-fold improvement achieved through fatty acid conjugation, D-amino acid substitution, cyclization, and depot formulations
Your optimal schedule depends on your unique health goals, lifestyle, and how your body responds to treatment, making it a dynamic journey rather than a rigid protocol
For type 2 diabetes, they are often added when first-line treatments such as metformin do not achieve adequate control
The first follow-up review is usually at week four to six
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