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An earlier 12-week trial in 300 obese adults produced a genuine positive signal the 1 mg daily dosing arm showed a statistically significant 2.8 kg mean weight loss versus 0.8 kg in the placebo group and that result is what justified moving into the larger Phase IIb trial
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The mechanisms that repair joint tissue can also feed tumor growth
Tendon and ligament injuries show early mobility improvement in weeks 2 to 4 but structural repair takes 3 to 6 months
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