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Position 2 (Alpha-aminoisobutyric acid, Aib) : The substitution of the natural amino acid at position 2 with the non-natural alpha-aminoisobutyric acid (Aib) residue is a well-established strategy for conferring resistance to dipeptidyl peptidase-4 (DPP-4) cleavage
Preclinical Evidence In rodent studies, SLU-PP-332 has demonstrated: 5070% increases in running endurance Improved insulin sensitivity and glucose control Reduced liver fat accumulation Elevated resting metabolism and enhanced fat oxidation These effects occur even in the absence of exercise, highlighting its potential as a research tool for studying metabolic disease, mitochondrial dysfunction, and exercise physiology
Florko, N
The role of nutrition in wound healing: an overview
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