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In some trials, up to 2540% of total weight lost was lean mass, not fat
Limitations of Current Research Many studies are preclinical Human mechanistic trials remain limited Microbiome responses vary individually Diet, sleep, stress, and medications influence outcomes GLP-1 regulation is multi-factorial The microbiome is one variable within a complex endocrine network
It works best as part of a long-term plan
Most existing methods rely on single, qualitative indicators, which provide limited insight into the overall quality
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