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(1) There are numerous issues that can cause appendix luminal blockage, including: Appendicoliths or fecaliths, which are calcified fecal deposits also known as appendix stones (this is more common in children than adults) (2) Intestinal worms or parasites, including pinworm ( Enterobius vermicularis ) Irritation and ulcers in the gastrointestinal (GI) tract resulting from long-lasting disorders, such as Crohns disease or ulcerative colitis Abdominal injury or trauma Enlarged lymph tissue of the wall of the appendix, which is typically the result of infections in the GI tract Benign or malignant tumors Various foreign objects, such as stones, bullets, air-gun pellets, and pins (3) Sometimes appendicitis is due to a viral, bacterial, or fungal infection that has spread to the appendix

Assessing pancreatic cancer risk associated with dipeptidyl peptidase 4 Inhibitors: data mining of FDA adverse event reporting system (FAERS)

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