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GLP-1 RA SmPCs (e.g., semaglutide) generally report no clinically relevant effect on overall drug exposure for most oral medicines, but individual monitoring remains prudent for narrow therapeutic index agents

It can feel like the stomach is tight, swollen, or full of gas

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Its chief executive Lisa Tookey said: Many patients approaching their target weight are already reducing doses on their own, without clinical guidance, but an oral option, prescribed and monitored properly, will give people a supported way to step down rather than stop abruptly or taper alone. The weight-loss pill also offers a more discreet option for patients who have hidden their treatment due to fears of judgement or stigma, said digital healthcare provider Voy