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Reduced tetrahydrofolate may serve as an acceptor of one-carbon units via nitrogen-5 and nitrogen-10
Still, the findings follow previous research that linked the drugs to a higher risk of osteoporosis-related fractures in older adults with Type 2 diabetes and reduced bone density
HbA1c, disease duration) and achieved AUC 0.81 in an independent test set, demonstrating utility in risk prediction rather than definitive diagnosis [58]
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