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notched a partial victory after a federal judge ruled the FDA arbitrarily determined that the drugmakers obesity and diabetes medicine, retatrutide, didnt qualify as a biological product
Importantly, an additional experiment showed that LASSS-treated BSA (after the removal of un-reacted LASSS) exhibited nitration resistance to the optimal peroxynitrite-treatment (1:2000 ratio), as shown in supplementary Figure 2, suggesting a model that LASSS-induced chemical modification mechanism exerts a nitration-inhibitory effect on a wide range of proteins susceptible to tyrosine nitration
[Abstract]2025 Jun 4;113(11):1708-1722.e5
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