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Images were processed using Fiji (ImageJ) software [29]

As shown in Figure 5E , DEG analysis revealed distinct gene expression profiles in MAC.2, with gene ontology pathway enrichment analysis indicating roles in bacterial response, response to lipopolysaccharides, response to molecules of bacterial origin, and cellular response to interleukin 1

609 PARP inhibitor Actovegin: Actovegin ameliorated sensory nerve conduction velocity (SNCV) and IENFD of experimental DN via mechanisms involving suppression of PARP activation