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In vitro barrier models using Caco-2 cells (gut epithelium) or brain endothelial cells could be employed to test the hypothesis that microbiota metabolites, such as butyrateeither administered directly or derived from patient-derived fecal microbiota culturescan strengthen epithelial and endothelial barrier function and reduce oxidative stress [40]
Glutamine, glycine, N-acetylcysteine, selenium, whey protein isolates with bonded cysteine, GSH and pro-GSH supplementation improves GSH deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, cognition and surfactant regeneration (301307)
Individuals with digestive issues like Crohns or celiac disease that affect nutrient absorption
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