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Current human evidence from large-scale studies and clinical trials has not demonstrated a clear or significant increase in thyroid cancer risk in humans using GLP-1 receptor agonists

Ann Neurol 1989;26:456

TABLE 2 outlines a practical approach based on the Three Es method that pharmacists can use to systematically educate patients and manage GI AEs associated with GLP-1 RA therapy

Or as one obesity researcher, who has associations with the drugmaker and did not feel comfortable speaking on the record, put it: Given the majority of people accessing these medications are women, and a significant portion will be of childbearing age, this needs more attention. Its not yet clear why the birth complications in animals arise