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The main cerebral target for THC is type-1 cannabinoid receptors (CB1R), which are widely expressed in the brain and regulate various functions including neurotransmitter release, neuro-astroglial communication, and cellular bioenergetic processes [29,30,31,32]

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Certain peptides, like angiogenesis peptides (peptide therapy, TB-500), should only be used in cycles because prolonged use may overstimulate blood vessel growth

Most patients who had some response to Saxenda see greater response to semaglutide