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CD8 + T lymphocytes can upregulate perforin expression and increase MMP activity, resulting in the airway and lung tissue destruction, as well as chemotactic activation of inflammatory cells through secretion of cytokines such as interferon, IL-12, TNF- and chemokines, exacerbating the inflammatory response

Sustained over years, however, chronic neuroinflammation becomes damaging in its own right, contributing to the accumulation of amyloid plaques and tau protein tangles that are the defining pathological features of Alzheimer's disease

Association of GCKR and MBOAT7 genetic polymorphisms with non-alcoholic fatty liver disease

There may be redness, itching, bruising, swelling, tenderness and warmth at the injection site