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These effects are likely partly due to local increases in extracellular glutamate causing excitotoxicity, and reduced trophic support [e.g., platelet-derived growth factor (PDGF)] from astrocytes (Tognatta et al., 2020)

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Several pharmaceutical giants are positioning themselves to challenge the incumbents

Delivery intervals are diverse, too, ranging from as little as two weeks to as long as six months