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The list price for brand-name GLP-1 medications is formidable

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A 2025 systematic review and meta-analysis published in Obesity Reviews analyzed eight randomized controlled trials that included participants with a BMI of 27 or higher (N=2,372) who had been on GLP-1 receptor agonist therapy and then stopped

Reduced postprandial cholecystokinin (CCK) secretion in patients with noninsulin-dependent diabetes mellitus: evidence for a role for CCK in regulating postprandial hyperglycemia