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Collectively, we uncovered a link between hepatic T3 action and glucose homeostasis through GLP-1, and provided evidence to show that the promising results observed for the liver-targeted TR agonist were not secondary to the known beneficial effects of weight loss on insulin sensitivity
These reports are consistent with its studied mechanisms including reduced neuroinflammation and BDNF upregulation
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2015;10(6):e0126769
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