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Basal insulin therapy should be considered when introducing dual or triple therapy and should be intensified adding a mealtime insulin or a GLP-1 RA when glycemic control needs to be optimized [1]
If you have obesity and are considering treatments that can lead to significant weight loss, you may be wondering how the two leading options compare: bariatric surgery, which permanently alters the digestive tract, versus powerful new appetite-suppressing medications like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound)
The role of the gut as a mediator is unequivocally demonstrated in models of chronic apical periodontitis (CAP), where P.g -induced CAP alters gut microbiota (increasing Lachnospiraceae , Ruminococcaceae ) and increases TMAO, thereby exacerbating aortic plaque formation
S2CID 25517996
