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The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance
They got some promising results
From a development scientists perspective, BPC-157 looks like a very promising mechanistic story with compelling preclinical proof-of-concept, but still at the interesting preclinical lead stage rather than known effective therapy. When comparing ARA-290 vs BPC-157 for injury recovery, ARA-290 currently leans toward nerve- and inflammation-focused recovery, while BPC-157 leans toward structural tissue repairmostly supported by animal data
A recent review highlighted concerns with IV use, including rare anaphylaxis and potential hepatotoxicity (PMC narrative review)
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