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3.7 Who Should Avoid Naltrexone/Bupropion (Contrave ) People taking opioids or with opioid dependence (due to risk of withdrawal) Anyone with a history of seizures or high seizure risk Individuals with uncontrolled hypertension Those under 25 years old with depression (due to suicidal ideation warning) 3.8 Who its best for / Ideal Candidates Individuals with strong cravings or emotional/reward-related eating , Those with mild depression symptoms

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81 Pregnancy complications The available data indicate that Factor V Leiden is associated with a 2- to 3-fold increased relative risk for pregnancy loss and possibly other complications such as preeclampsia, intrauterine growth restriction and placental abruption

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