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MnO x nanospikes, as TME-responsive nano-adjuvants and immunogenic cell death drugs, were also designed for cancer nanovaccine-based immunotherapy ( 2 and Fe 3 O 4 were co-loaded on to dendritic mesoporous silica NPs, researchers showed that these particles can achieve tumor specialized localization and induction of Fenton reaction, thus triggering ferroptosis (Li and Rong, 2020)

Abstract The prevalence of type 2 diabetes (T2D) is increasing worldwide, with many patients developing long-term complications that affect their cardiovascular, urinary, alimentary, and other systems