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GLP-1 dosing should not require changes to HRT dosing, and vice versa, unless the oral absorption issue applies

Compared with other non-insulin hypoglycemic drugs, it can not only effectively reduce blood glucose and glycosylated hemoglobin (HbA1c), but also protect cardiovascular system, nervous system and kidney function without causing hypoglycemia and weight gain

In many experimental systems, additional factorssuch as miRNA delivery or biomolecular coatingsmay contribute synergistically to macrophage modulation ( 2 from these combined approaches is essential for clarifying its mechanistic effect and optimizing therapeutic design

Dosing: 4mg initially, then 2mg after each loose stool