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The long-acting compound contains a reactive drug-affinity-complex groupcommonly shortened to DACdesigned to bind covalently to endogenous albumin after administration
Specifically, the 1,2,3-trihydroxyphenyl group in EGCG has a high affinity to tyrosinase, which allows HA_E to be oxidized and cross-linked with HA_T to form an adhesive hydrogel (HA_TE)
In contrast, a longer recovery period of 5 h post pre-cutting was required for the assessment of small molecules-activated gene expression levels
This is not a drug and so there are no known contradictions and precautions to be taken into consideration
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