[1] Patients should report symptoms such as a lump in the neck, persistent hoarseness, trouble swallowing, or shortness of breath
Straining or Hard Stools : If you find yourself straining excessively during bowel movements, or if the stools are hard and difficult to pass, a laxative may help soften them, making bowel movements easier and less painful
Seek medical advice for heavy bleeding soaking through protection hourly, bleeding lasting over 7 days, postmenopausal bleeding, persistent bleeding between periods, amenorrhoea for 3+ months, or severe pelvic pain
The WHI observational study found that estrogen-plus-progestogen HRT increased invasive breast cancer risk with a hazard ratio of 1.24 (95% CI 1.01 to 1.54) after 5.6 years of median follow-up [12]