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Moreover, transgenic mice over-expressing SDF-1 become resistant to streptozotocin-induced diabetes (61), further suggesting that SDF-1 may have some metabolic effects

Introduction Nonalcoholic fatty liver disease (NAFLD) is becoming an increasingly prevalent form of chronic liver disease in the Western world

More human trials are needed, but the early signals and the depth of preclinical evidence are why BPC-157 remains the most widely used recovery peptide in clinical practice

These benefits are particularly evident in conditions like nonalcoholic steatohepatitis (NASH), where GLP-1RAs alleviate inflammation and boost insulin sensitivity, leading to improved hepatic glucose management and reduced steatosis (Zheng et al., 2024)