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High circulating ADM was strongly associated with disease severity, organ failure, vasopressor need, and 30-day mortality, highlighting its value as both a biomarker and predictor of outcome in septic patients (Lundberg et al., 2020)
Amino acid metabolism and pulmonary fibrosis Arginine plays a key role in pulmonary fibrosis Arginineproline metabolism in pulmonary fibrosis Emerging evidence indicates that the arginineproline metabolic axis is notably upregulated in pulmonary fibrosis, contributing to excessive ECM deposition and disease progression [66,67,68,69,70]
The formation of DON-GSH conjugates was also observed
Citrulline is found in high concentration in the liver and is not a component of any major proteins or enzymes, and therefore not much information is available
