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Generalized Anxiety Disorder (GAD) and Comorbid Major Depression with GAD Are Characterized by Enhanced Nitro-oxidative Stress, Increased Lipid Peroxidation, and Lowered Lipid-Associated Antioxidant Defenses
Our findings in brain organoids with PSEN1 mutation complement well the results in human cortical organoids challenged with A that showed an increased expression of ferroptosis-promoting factors like Phkg243, Txnrd144 and Pparg42 [50]
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