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Importantly, GIP receptor sensitivity is impaired in prolonged hyperglycemic states due to receptor downregulation but can be restored upon achieving euglycemia through complementary GLP-1 action [38,39]

The two have never been compared directly

Understanding what drug screens actually detectand why tirzepatide isn't among themcan provide reassurance for patients undergoing employment testing, pre-operative screening, or routine clinical assessments while using this FDA-approved prescription therapy