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Note that prescription options like domperidone should be used at the lowest effective dose for the shortest duration due to cardiac side effect risks, and metoclopramide is typically limited to short-term use (5 days) due to neurological adverse effects [10] For constipation, consider osmotic laxatives (e.g., macrogol) or stimulant laxatives if needed, but avoid long-term use without medical advice Do not stop semaglutide without medical advice

and Paul Newhouse, MD , director of the Vanderbilt Center for Cognitive Medicine

If a pen becomes frozen, it must be discarded safely, even if it appears normal after thawing

Instead, gently swirl the vial or roll it between your hands until the powder has completely dissolved into the solution