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A BMI of 30 or higher (which is the clinical threshold for obesity)
GSTM2 modulates size and number of LDs in HepG2 cells To further investigate the potential regulatory mechanism, we generated a GSTM2 -knockdown stable cell line (shGSTM2-HepG2) that expressed less GSTM2 mRNA and protein than control cells (shNC-HepG2) (Fig
It was developed by a research team at Novo Nordisk and first described in detail in the peer-reviewed literature in 2015 [1]
Lipofuscin is commonly observed in human liver biopsies from patients with CLD 8,9 , which can result from various insults such as high-fat diet 10 , drug 11 , and viral infection 5
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