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However, the studies in HGF-A knockout mice have shown that HGF-A gene deletion does not affect liver regeneration (Fukushima et al., 2018)

doi:10.1016/0895-4356(94)90117-1 Franco R, Schoneveld OJ, Pappa A, Panayiotidis MI

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However, not everyone converts synthetic forms efficiently, particularly those with higher metabolic stress, liver strain, or certain genetic variations including the MTHFR mutation