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Additionally, the expression of tight junction-associated proteins in colonic tissues was significantly upregulated after the intervention, suggesting that the intervention may attenuate damage to intercellular tight junctions triggered by inflammatory factors, thereby protecting the intestinal mucosal barrier integrity

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RGDV Pns11 antagonises E3-mediated ubiquitinated degradation of Pelo We then investigated whether E3 mediated Pelo ubiquitinated degradation