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4.3.2 The MMPM+HFD + ADF model rats exhibit significant alterations in fatigue-related serum biochemical metabolic indicators The findings from the analysis of serum biochemical metabolic indicators demonstrated notable changes in fatigue-related parameters in the MMPM+HFD + ADF model rats, suggesting substantial energy expenditure, reduced glycogen reserves, and disrupted glucose metabolism in these rats
This is not catastrophic
Use in pregnancy, lactation and paediatric exposure has not been characterised in any published dataset, and no developmental-toxicology study has been formally reported
