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Indeed, HFD feeding markedly increased the expression of ALDH1A3, which is a well-established marker of -cell dedifferentiation [26], while all the drug treatments reversed the upregulation of ALDH1A3 in HFD-fed mice, indicating a rescue of -cell dedifferentiation (Fig

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10.1074/jbc.M106838200 21 DalakliogluS.GencG

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