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10.1016/S0140-6736(99)00641-8 Lancet 36 FournierA
One suggested practice to managing GI AEs is the Three Es method, which comprises 1) education and explanation, 2) escalation to an appropriate dose, and 3) effective management of GI AEs
Among these, compound 2 (Figure 3) demonstrated the strongest inhibitory activity, with an IC 50 value of 6.57 M (94)
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