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Ibuprofen hepatic encephalopathy, hepatomegaly, gastric lesion and gastric pentadecapeptide BPC 157 in rats

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BPC-157 enhances eNOS phosphorylation at serine 1177 through Akt-dependent mechanisms, quantifiable using luminescent kinase activity assays and nitrite/nitrate colorimetric detection methods

These molecules can be derived from natural sources, including food, venoms, and marine organisms [16, 17], or synthesized through enzymatic hydrolysis and recombinant DNA technologies [18]