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In cases where peripheral neuropathy is the presenting feature, evaluation for common causes (eg, impaired glucose metabolism, hypothyroidism) is necessary, keeping in mind that autoimmune disorders can present with combinations of disorders (eg, pernicious anemia, autoimmune thyroid dysfunction, and type 1 diabetes)
By reducing levels of these mediators, cold therapy creates conditions more favorable for tissue preservation
So the benefit is real, but it is indirect and it depends on whether you were low to begin with
What This Means for Physicians and Medical Practices Regulatory shifts require immediate practice-level adjustments to mitigate legal and operational risks
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