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semaglutide has more extensive cardiovascular outcome data Cardiovascular Disease: Semaglutide has proven heart benefits in SELECT trial Kidney Disease: Dosing adjustments may be needed for both Gastrointestinal Issues: Pre-existing GI problems may influence tolerance Lifestyle Factors: Neither medication works without lifestyle changes

Biochemical rebalancing through supplementation can produce systemic effects relevant to both physical and neurocognitive domains 46,47

doi: 10.1016/S1474-4422(08)70167-4 68 LeeC.YuD.KimH

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