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Horizon Therapeutics (Tepezza) integration delivering growth Key Market Developments 20222026 Semaglutide became the world's highest-revenue drug (2024): Combined Ozempic + Wegovy sales of ~USD 26 billion in 2024 made semaglutide the best-selling drug globally displacing Keytruda and Humira

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In another study, curcumin increased the expression of the small non-coding RNA miR181b, which then downregulated proinflammatory cytokines , CXCL1 and CXCL2, as well as MMPs, thereby reducing the metastatic potential of breast cancer cells