A couple of studies have investigated its effects when administered intravenously
Aetna may provide coverage for the following weight loss injections when medically necessary and with prior authorization: Approved for chronic weight management in adults with a BMI of 30 or greater, or 27 or greater with at least one weight-related comorbidity like type 2 diabetes, high blood pressure, or sleep apnea
At the systemic level, GLP-1 RAs improve insulin sensitivity in peripheral tissues (muscle, adipose), reduce circulating free fatty acid flux to the liver, suppress hypothalamic appetite circuits to promote weight loss, and lower systemic pro-inflammatory cytokines (TNF-, IL-1, IL-6), thereby reducing the hepatic inflammatory milieu indirectly [7,26,30]
Good protein sources include fish, poultry, meat, strained (Greek-style) yogurt, cottage cheese, cheese, legumes, soy, eggs and more