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Experimental studies have demonstrated measurable increases in circulating growth hormone and downstream IGF-1 signaling in controlled settings, with preserved natural GH pulsatility and no observed pituitary desensitization at standard research doses [2]
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Naguib M et al (2004): Posttetanic potentiation and fade in the response to tetanic and train-of-four stimulation during succinylcholine-induced block
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