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Treatment is most effective in early stages, generally Stage 1 to early Stage 3, when most follicles are still active
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glutathione helps manage this by protecting cells from damage
83 Similarly, in pancreatic adenocarcinoma (PAAD), lactylation of NMNAT1 at lysine 128 enhances its nuclear localization and enzymatic activity in PAAD cells, activating the NAD + salvage pathway and promoting cell survival, linking Kla to NAD + metabolism
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