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[5] [6] Soluble fibre (found in oats, beans, lentils, and fruits) helps soften stools, whilst insoluble fibre (in wholegrain bread, brown rice, and vegetables) adds bulk and promotes transit

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Similarly, tirzepatide, a dual GLP-1R and GIP receptor agonist, does not seem to cross the BBB efficiently (Rhea et al., 2024)

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