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Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress
Patients are more likely to choose drugs with lower cost sharing (in consultation with their physicians when all else is equal or similar between drugs), so the manufacturer has an incentive to provide a higher rebate to ensure that its drug has the lowest cost sharing among competitors and is thus more attractive to the patient
- Fasting glucose and a basic lipid panel (AOD-9604 did not raise glucose or worsen lipids in trials, but baseline confirmation is useful)
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These doses are sub-therapeutic, meaning they fall below the level that clinical trials have demonstrated to produce statistically significant weight loss
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