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This strategy has been applied to dulaglutide, where two GLP-1 molecules are fused to the Fc fragment of IgG4, increasing the half-life while reducing the renal elimination due to the increased molecular weight
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For now, Low Wang is not recommending Mounjaro for patients who want to lose weight but dont have diabetes
Yes, burping is a very common and expected side effect during the first 4-8 weeks of GLP-1 therapy as your stomach adjusts to slower gastric emptying
Both amino acids are involved in complex metabolic pathways
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