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They may only affect pills and only at starting and dosage increases, but the data are sparse
In the early 2000s there was a similar trend: Heroin chick
The standard 0.5mg daily dose provides optimal risk-benefit ratio according to clinical trials, though 1.0mg shows stronger effects with proportionally higher risks
In the FINE-HEART pooled analysis of these three large clinical trials, finerenone also reduced the risks of HHF, composite kidney outcome without macroalbuminuria, MACE, and all cause death [55]
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