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Adverse Reactions in Patients for Weight Reduction and Long-Term Maintenance Pool of Placebo-Controlled Weight Reduction Trials in Adults with Obesity or Overweight, with or without Type 2 Diabetes (Study 1 and Study 2) ZEPBOUND was evaluated for safety in a pool of two randomized, double-blind, placebo-controlled trials that included 2,519 adult patients with obesity or overweight treated with ZEPBOUND for up to 72 weeks and a 4-week off drug follow-up period (Study 1 and Study 2) [see Clinical Studies (14.1)]

Understanding where proteins are expressed throughout the body is critical for selecting better drug targets

When cagrilintide binds these receptors in brain regions including the area postrema and dorsal vagal complex, it triggers a cascade of satiety signals

Interventional measures may interfere with the bodys immune regulatory function, thereby increasing the risk of infection or causing immune disorders