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Semaglutide had a consistent beneficial effect on percentage change in body weight across diuretic use categories (adjusted mean difference ranged from 8.8 to 6.9 percent for no diuretics to the highest loop diuretic dose category)
People with a history of blood clots or clotting problems, or who take blood thinners, should also be cautious
Additionally, rapid reduction in HbA1c with semaglutide has been associated with worsening of diabetic retinopathy in patients with pre-existing retinopathy
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